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A
Coconut Oil
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A1
Evangelista MT, Abad-Casintahan F, et al. The effect of topical virgin coconut oil on SCORAD index, transepidermal water loss, and skin capacitance in mild to moderate pediatric atopic dermatitis: a randomized, double-blind, clinical trial. Int J Dermatol. 2014 Jan;53(1):100-108.
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B
Herbs
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B1
Cheng HM, Chiang LC, et al. The efficacy and safety of a Chinese herbal product (Xiao-Feng-San) for the treatment of refractory atopic dermatitis: a randomized, double-blind, placebo-controlled trial. Int Arch Allergy Immunol. 2011;155(2):141-148.
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B2
Gu S, Yang AW, et al. Chinese herbal medicine for atopic eczema. Cochrane Database Syst Rev. 2013 Sep 10;(9):CD008642.
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B3
Gu S, Yang AW, et al. Topical application of Chinese herbal medicine for atopic eczema: a systematic review with a meta-analysis. Dermatology. 2014;228(4):294-302.
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C
Probiotics
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C1
Michail SK, Stolfi A, et al. Efficacy of probiotics in the treatment of pediatric atopic dermatitis: a meta-analysis of randomized controlled trials. Ann Allergy Asthma Immunol. 2008 Nov;101(5):508-516.
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C2
Gerasimov SV, Vasjuta VV, et al. Probiotic supplement reduces atopic dermatitis in preschool children: a randomized, double-blind, placebo-controlled, clinical trial. Am J Clin Dermatol. 2010;11(5):351-361.
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C3
Woo SI, Kim JY, et al. Effect of Lactobacillus sakei supplementation in children with atopic eczema-dermatitis syndrome. Ann Allergy Asthma Immunol. 2010 Apr;104(4):343-348.
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C4
Drago L, Iemoli E, et al. Effects of Lactobacillus salivarius LS01 (DSM 22775) treatment on adult atopic dermatitis: a randomized placebo-controlled study. Int J Immunopathol Pharmacol. 2011 Oct-Dec;24(4):1037-1048.
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C5
Wu KG, Li TH, et al. Lactobacillus salivarius plus fructo-oligosaccharide is superior to fructo-oligosaccharide alone for treating children with moderate to severe atopic dermatitis: a double-blind, randomized, clinical trial of efficacy and safety. Br J Dermatol. 2012 Jan;166(1):129-136.
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C6
Drago L, Toscano M, et al. Changing of fecal flora and clinical effect of L. salivarius LS01 in adults with atopic dermatitis. J Clin Gastroenterol. 2012 Oct;46 Suppl:S56-63.
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C7
Iemoli E, Trabattoni D, et al. Probiotics reduce gut microbial translocation and improve adult atopic dermatitis. J Clin Gastroenterol. 2012 Oct;46 Suppl:S33-40.
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C8
Han Y, Kim B, et al. A randomized trial of Lactobacillus plantarum CJLP133 for the treatment of atopic dermatitis. Pediatr Allergy Immunol. 2012 Nov;23(7):667-673.
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C9
Kim, SO, Ah YM, et al. Effects of probiotics for the treatment of atopic dermatitis: a meta-analysis of randomized controlled trials. Ann Allergy Asthma Immunol. 2014 Aug;113(2):217-226.
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C10
Allen SJ, Jordan S, et al. Probiotics in the prevention of eczema: a randomised controlled trial. Arch Dis Child. 2014 Nov;99(11):1014-1019.
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C11
Cuello-Garcia CA, Brożek JL, et al. Probiotics for the prevention of allergy: A systematic review and meta-analysis of randomized controlled trials. J Allergy Clin Immunol. 2015 Oct;136(4):952-961.
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C12
Zuccotti G, Meneghin F, et al. Probiotics for prevention of atopic diseases in infants: systematic review and meta-analysis. Allergy. 2015 Nov;70(11):1356-1371.
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C13
Cabana MD, McKean M, et al. Early Probiotic Supplementation for Eczema and Asthma Prevention: A Randomized Controlled Trial. Pediatrics. 2017 Sep;140(3). pii: e20163000.
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C14
Huang R, Ning H, et al. Probiotics for the Treatment of Atopic Dermatitis in Children: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Front Cell Infect Microbiol. 2017 Sep 6;7:392.
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C15
Wu YJ, Wu WF, et al. Evaluation of efficacy and safety of Lactobacillus rhamnosus in children aged 4-48 months with atopic dermatitis: An 8-week, double-blind, randomized, placebo-controlled study. J Microbiol Immunol Infect. 2017 Oct;50(5):684-692.
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C16
Wickens K, Barthow C, et al. Maternal supplementation alone with Lactobacillus rhamnosus HN001 during pregnancy and breastfeeding does not reduce infant eczema. Pediatr Allergy Immunol. 2018 May;29(3):296-302.
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C17
Zhao M, Shen C, et al. Treatment efficacy of probiotics on atopic dermatitis, zooming in on infants: a systematic review and meta-analysis. Int J Dermatol. 2018 Jun;57(6):635-641.
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C18
Szajewska H, Horvath A. Lactobacillus rhamnosus GG in the Primary Prevention of Eczema in Children: A Systematic Review and Meta-Analysis. Nutrients. 2018 Sep 18;10(9). pii: E1319.
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C19
Makrgeorgou A, Leonardi-Bee J, et al. Probiotics for treating eczema. Cochrane Database Syst Rev. 2018 Nov 21;11:CD006135.
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D
Supplements
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D1
Javanbakht MH, Keshavarz SA, et al. Randomized controlled trial using vitamins E and D supplementation in atopic dermatitis. J Dermatolog Treat. 2011 Jun;22(3):144-150.
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D2
Bamford JT, Ray S, et al. Oral evening primrose oil and borage oil for eczema. Cochrane Database Syst Rev. 2013 Apr 30;(4):CD004416.
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D3
Camargo CA Jr, Ganmaa D, et al. Randomized trial of vitamin D supplementation for winter-related atopic dermatitis in children. J Allergy Clin Immunol. 2014 Oct;134(4):831-835.e1.
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D4
Kim G, Bae JH. Vitamin D and atopic dermatitis: a systematic review and meta-analysis. Nutrition. 2016 Sep;32(9):913-920.
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D5
Kim MJ, Kim SN, et al. Vitamin D Status and Efficacy of Vitamin D Supplementation in Atopic Dermatitis: A Systematic Review and Meta-Analysis. Nutrients. 2016 Dec 3;8(12). pii: E789.
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D6
Sánchez-Armendáriz K, García-Gil A, et al. Oral vitamin D3 5000 IU/day as an adjuvant in the treatment of atopic dermatitis: a randomized control trial. Int J Dermatol. 2018 Dec;57(12):1516-1520.